Introduction: Lesions which make the jaws swell are comparatively more common in the developing world than they are elsewhere. Apart from trauma, the jaws can swell as the result of conditions which include: (1) Infection: an alveolar abscess, a dental sinus which is sometimes misdiagnosed as an early jaw tumour, and osteomyelitis (2)cysts (3) Tumours: Burkitt's lymphoma, ameloblastoma, carcinoma, salivary tumours, and giant cell tumours (4) A complex group of fibro-osseous lesion.

Case Report: A 16-year-old female patient presented to outpatient department with chief complaints of right sided cheek swelling for past four months which was bony hard, non-tender and fixed. The CT Alveolus region revealed a large expansile lytic lesion in right posterior region of mandible with severe thinning of cortex with multiple areas of cortical break without evidence of soft tissue infiltration arising possibility of Dentigerous cyst. Right hemimandibulectomy with plating was done and specimen was sent for histopathological examination which revealed swelling as Ameloblastoma-Unicystic variant.

Conclusion: Ameloblastomas are most common neoplasm of Odontogenic origin. They usually occur in 3rd to 5th decade, rarely in children and elderly. Mostly occurs in posterior region of Mandible. Ameloblastomas are locally invasive tumors and do not metastasize. Ameloblastomas are slow growing and asymptomatic leading to facial deformity and jaw expansion. Wide surgical excision is the treatment of choice.




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